Parameter
| Biomarker | pro-BDNF | Full name | Pro-Brain-Derived Neurotrophic Factor | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Prognosis, Disease Monitoring |
| Disease | Depression | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Plasma (ELISA) | ||
| Pathobiological Mechanisms | An increased pro-BDNF/BDNF ratio inhibits neuroregeneration and promotes neuronal apoptosis through the p75NTR receptor. | ||||
| Clinical Availability Status | Research Validation Stage | ||||
| Notes and Dynamics | Positively correlated with suicidal ideation (ratio >1.5 indicates high risk); a decreased ratio after treatment suggests a good prognosis. | ||||