Parameter
| Biomarker | AEA | Full name | Anandamide | Molecular Type | Lipid (Endocannabinoid) |
|---|---|---|---|---|---|
| Molecular Formula | C22H37NO2 | Molecular Weight | 347.53 g/mol | Core Functional Dimensions | Diagnosis, Subtype Differentiation |
| Disease | Depression | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Plasma/Serum (Liquid Chromatography-Tandem Mass Spectrometry LC-MS/MS) | ||
| Pathobiological Mechanisms | Endocannabinoid system dysfunction; decreased AEA levels weaken the stress-buffering effect and exacerbate anxiety-depression comorbidity symptoms. | ||||
| Clinical Availability Status | Research Stage | ||||
| Notes and Dynamics | Negatively correlated with anxiety symptoms; moderate-intensity exercise (e.g., 30-minute cycling) can upregulate its levels to improve mood. | ||||