Parameter
| Biomarker | miR-146a | Full name | MicroRNA-146a | Molecular Type | Non-coding RNA |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Disease Monitoring, Prognosis |
| Disease | Depression | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Plasma Extracellular Vesicles (Quantitative Real-Time PCR qRT-PCR) | ||
| Pathobiological Mechanisms | Downregulates the expression of pro-inflammatory factors (IL-6/TNF-α), regulates neuroinflammatory responses, and improves synaptic plasticity. | ||||
| Clinical Availability Status | Research Stage | ||||
| Notes and Dynamics | Expression is upregulated 1.8-fold after 4 weeks of antidepressant treatment, and can predict treatment response. | ||||