Parameter
| Biomarker | Melatonin | Full name | Melatonin | Molecular Type | Hormone |
|---|---|---|---|---|---|
| Molecular Formula | C13H16N2O2 | Molecular Weight | 232.28 g/mol | Core Functional Dimensions | Diagnosis, Disease Monitoring |
| Disease | Brain | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Saliva/Plasma (ELISA, LC-MS/MS) | ||
| Pathobiological Mechanisms | Circadian rhythm disturbance leads to decreased melatonin secretion, weakening its anti-inflammatory, antioxidant, and neuroprotective effects. | ||||
| Clinical Availability Status | Research Stage | ||||
| Notes and Dynamics | Nighttime melatonin <10pg/mL is positively correlated with depression-related insomnia symptoms; exogenous supplementation can improve sleep quality. | ||||