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645

Parameter
Biomarker GAD65 Ab Full name GAD65 antibody Molecular Type Antibodies (proteins)
Molecular Formula Macromolecule Molecular Weight / Core Functional Dimensions Susceptibility to diagnose,
Disease Diabetes Mellitus Disease Subtypes /
Organ Pancreas Test Sample / Technology Platform Serum (ELISA, electrochemical luminescence method)
Pathobiological Mechanisms Autoimmune antibodies against pancreatic beta cells, leading to insulin secretion defects
Clinical Availability Status Clinical routine classification diagnosis for T1DM and LADA, high-risk groups preferred antibody screening index
Notes and Dynamics Key core autoantibodies in type 1 diabetes, LADA diagnosis markers, used in high-risk population screening

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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