Parameter
| Biomarker | IA-2 Ab | Full name | Islet antigen-2 antibody (tyrosine phosphatase antibody) | Molecular Type | Antibodies (protein) |
|---|---|---|---|---|---|
| Molecular Formula | Macromolecule | Molecular Weight | / | Core Functional Dimensions | Diagnosis, prognosis, |
| Disease | Diabetes Mellitus | Disease Subtypes | / | ||
| Organ | Pancreas | Test Sample / Technology Platform | Serum (Immunoassay) | ||
| Pathobiological Mechanisms | Autoimmune antibodies targeting islet beta cells, accelerate the beta cell damage | ||||
| Clinical Availability Status | Clinical with joint detection in order to enhance T1DM GAD65 antibody specificity, detection application less alone | ||||
| Notes and Dynamics | Combined detection with GAD65 antibody can improve the diagnostic specificity of T1DM | ||||