Parameter
| Biomarker | ZnT8 Ab | Full name | ZnT8 antibody (zinc transporter 8 antibody) | Molecular Type | Antibodies (protein) |
|---|---|---|---|---|---|
| Molecular Formula | Macromolecule | Molecular Weight | / | Core Functional Dimensions | Diagnosis, susceptibility |
| Disease | Diabetes Mellitus | Disease Subtypes | / | ||
| Organ | Pancreas | Test Sample / Technology Platform | Serum (Immunoassay) | ||
| Pathobiological Mechanisms | Autoimmune antibodies attack islet β-cell zinc transporters and participate in β-cell dysfunction | ||||
| Clinical Availability Status | Clinical as auxiliary indexes in T1DM parting, combining with other autoantibodies, the detection alone lack of specificity | ||||
| Notes and Dynamics | Sustainability in LADA is higher than adult onset of type 1 diabetes, no clear specific clinical features | ||||