Parameter
| Biomarker | miR-27a/miR-141-3p | Full name | microRNA-27a / microRNA-141-3p | Molecular Type | Nucleic acid (miRNA, EV source) |
|---|---|---|---|---|---|
| Molecular Formula | Macromolecule | Molecular Weight | / | Core Functional Dimensions | Susceptibility to diagnose, |
| Disease | Diabetes Mellitus | Disease Subtypes | / | ||
| Organ | Systemic | Test Sample / Technology Platform | Plasma/serum (qRT - PCR) | ||
| Pathobiological Mechanisms | By regulating the insulin signaling pathway, it exacerbates insulin resistance | ||||
| Clinical Availability Status | At the clinical validation stage, has not yet been incorporated into clinical guidelines, the lack of standardized testing method | ||||
| Notes and Dynamics | EV carry miRNAs are potential biomarkers of insulin resistance | ||||