Parameter
| Biomarker | BRAF V600E Mut | Full name | B-Raf Proto-Oncogene V600E Mutation | Molecular Type | Gene Mutation |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Prediction |
| Disease | Epilepsy | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Tumor Tissue (NGS, ARMS-PCR) | ||
| Pathobiological Mechanisms | Activates the MAPK/mTOR pathway, simultaneously inducing neuronal epileptogenesis and glial tumor proliferation. | ||||
| Clinical Availability Status | Under clinical validation | ||||
| Notes and Dynamics | Highly prevalent in pediatric low-grade brain tumors (e.g., ganglioglioma); BRAF inhibitors can simultaneously inhibit tumor growth and seizures. | ||||