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518

Parameter
Biomarker miR-128 Full name MicroRNA-128 Molecular Type MicroRNA
Molecular Formula / Molecular Weight / Core Functional Dimensions Prognosis, Monitoring
Disease Epilepsy Disease Subtypes /
Organ Brain Test Sample / Technology Platform Plasma/Cerebrospinal Fluid (qRT-PCR)
Pathobiological Mechanisms Targets and regulates neuron excitability-related genes (e.g., SOX9), downregulated expression is associated with hippocampal sclerosis and epilepsy recurrence.
Clinical Availability Status Research validation stage
Notes and Dynamics Positively correlated with postoperative recurrence risk in TLE patients; plasma levels can be used as a non-invasive recurrence monitoring indicator.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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