Parameter
| Biomarker | miR-146a | Full name | MicroRNA-146a | Molecular Type | MicroRNA |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Prognosis, Monitoring |
| Disease | Epilepsy | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Plasma/Cerebrospinal Fluid (qRT-PCR) | ||
| Pathobiological Mechanisms | Regulates the TLR4/NF-κB pathway, upregulated expression exacerbates neuroinflammation, promoting epilepsy progression. | ||||
| Clinical Availability Status | Research validation stage | ||||
| Notes and Dynamics | Meta-analysis shows that CSF miR-146a levels in TLE patients are elevated by 1.8 times, correlated with disease severity. | ||||