Parameter
| Biomarker | miR-29a/b | Full name | microRNA-29a / microRNA-29b | Molecular Type | Nucleic acid (miRNA) |
|---|---|---|---|---|---|
| Molecular Formula | Macromolecule | Molecular Weight | / | Core Functional Dimensions | Diagnosis, risk assessment |
| Disease | Diabetes Mellitus | Disease Subtypes | / | ||
| Organ | Placenta/Systemic | Test Sample / Technology Platform | Serum (qRT - PCR) | ||
| Pathobiological Mechanisms | It regulates glucose metabolism and insulin sensitivity, and its expression is abnormal during pregnancy | ||||
| Clinical Availability Status | Validation phase in clinical research, diagnosis of GDM AUC 0.944 joint detection, the accuracy is better than that of single index, but has not yet been incorporated into the clinical guidelines | ||||
| Notes and Dynamics | The diagnostic accuracy of combined detection was better than that of single index (AUC 0.944). | ||||