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522

Parameter
Biomarker S100B Full name S100 Calcium-Binding Protein B Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Prognosis, Monitoring
Disease Epilepsy Disease Subtypes /
Organ Brain Test Sample / Technology Platform Serum (ELISA)
Pathobiological Mechanisms Released after astrocyte activation, involved in neuroinflammation and blood-brain barrier disruption, reflecting the degree of brain injury.
Clinical Availability Status Under clinical validation
Notes and Dynamics Serum S100B peaks within 24 hours after TLE seizures, and levels are positively correlated with the degree of hippocampal sclerosis.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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