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526

Parameter
Biomarker Ki-67 Full name Ki-67 Protein Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Prognosis, Risk Stratification
Disease Epilepsy Disease Subtypes /
Organ Brain Test Sample / Technology Platform Tumor Tissue (Immunohistochemistry)
Pathobiological Mechanisms Reflects tumor proliferation activity; higher expression indicates more significant intracerebral microenvironment disorder and increased epilepsy onset risk.
Clinical Availability Status Under clinical validation
Notes and Dynamics In WHO grade II glioma patients with Ki-67 index > 5%, the postoperative epilepsy recurrence risk is increased by 2 times.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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