Parameter
| Biomarker | Abnormal Gut Microbiota (e.g., Decreased Bifidobacterium) | Full name | Abnormal Gut Microbiota Abundance (e.g., Decreased Bifidobacterium) | Molecular Type | Microbial Community |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Risk Stratification, Monitoring |
| Disease | Epilepsy | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Feces (16S rRNA Sequencing, Metagenomic Sequencing) | ||
| Pathobiological Mechanisms | Imbalance of gut microbiota metabolites (e.g., short-chain fatty acids) regulates neuroinflammation and excitability through the gut-brain axis. | ||||
| Clinical Availability Status | Research stage | ||||
| Notes and Dynamics | Probiotic intervention can improve seizure frequency in some patients; Bifidobacterium preparations have entered clinical phase I. | ||||