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530

Parameter
Biomarker TSPO Full name 18kDa Transporter Protein Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis, Monitoring
Disease Epilepsy Disease Subtypes /
Organ Brain Test Sample / Technology Platform Brain (PET Imaging)
Pathobiological Mechanisms A specific marker of activated microglia, reflecting the degree of neuroinflammation.
Clinical Availability Status Research validation stage
Notes and Dynamics TSPO PET uptake in the hippocampus of TLE patients is positively correlated with seizure frequency, which can assess disease activity.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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