Parameter
| Biomarker | AQP4 | Full name | Aquaporin 4 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Prognosis |
| Disease | Epilepsy | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Tumor Tissue (Immunohistochemistry) | ||
| Pathobiological Mechanisms | Abnormal expression of aquaporin leads to intracerebral edema, disrupts the neuronal microenvironment, and induces epilepsy. | ||||
| Clinical Availability Status | Research validation stage | ||||
| Notes and Dynamics | The incidence of epilepsy in GBM patients with high AQP4 expression reaches 68%, positively correlated with the degree of cerebral edema. | ||||