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532

Parameter
Biomarker IL-6 Full name Interleukin-6 Molecular Type Cytokine
Molecular Formula / Molecular Weight / Core Functional Dimensions Prediction, Monitoring
Disease Epilepsy Disease Subtypes /
Organ Brain Test Sample / Technology Platform Serum/Cerebrospinal Fluid (ELISA, qPCR)
Pathobiological Mechanisms Activates the JAK-STAT pathway, promotes neuroinflammation, and reduces ASM sensitivity.
Clinical Availability Status Under clinical validation
Notes and Dynamics CSF IL-6 levels in drug-refractory epilepsy patients are 2.3 times higher than those in sensitive patients; IL-6 receptor antagonists can improve seizures in some patients.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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