Parameter
| Biomarker | GFAP | Full name | Glial Fibrillary Acidic Protein | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Monitoring, Prognosis |
| Disease | Multiple Sclerosis | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Serum / CSF (Simoa) | ||
| Pathobiological Mechanisms | A marker of astrocyte activation, involved in blood-brain barrier injury and inflammatory response, associated with gray matter lesions. | ||||
| Clinical Availability Status | Research validation / early clinical use: Lower specificity than NfL; combined detection improves prognostic value. | ||||
| Notes and Dynamics | Associated with chronic active lesions, a potential monitoring indicator for progressive MS. | ||||