Parameter
| Biomarker | CSF OCBs | Full name | Cerebrospinal Fluid Oligoclonal Bands | Molecular Type | Protein (Immunoglobulin) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Susceptibility |
| Disease | Multiple Sclerosis | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | CSF (Isoelectric Focusing + Immunoblotting) | ||
| Pathobiological Mechanisms | A marker of intrathecal immunoglobulin synthesis, reflecting local autoimmune response, associated with MS conversion risk. | ||||
| Clinical Availability Status | Clinical validation / guideline recommendation: A core indicator for MS diagnosis; negative results indicate low conversion risk. | ||||
| Notes and Dynamics | Appear in some patients in the late stage, can replace evidence of spatial dissemination; kappa free light chain index can be used as an alternative indicator. | ||||