Parameter
| Biomarker | MOG-IgG | Full name | Myelin Oligodendrocyte Glycoprotein Antibody | Molecular Type | Protein (Antibody) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Differential Diagnosis |
| Disease | Multiple Sclerosis | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Serum (Cell-based Assay) | ||
| Pathobiological Mechanisms | Targets myelin MOG protein, mediates complement-dependent demyelination, associated with RIS conversion to clinically confirmed MS. | ||||
| Clinical Availability Status | Clinical validation / guideline recommendation: A core indicator for distinguishing RIS from MOGAD. | ||||
| Notes and Dynamics | High titers indicate MOG-related disease; low titers require combination with clinical and MRI features for judgment. | ||||