Parameter
| Biomarker | CSF KFLC Index | Full name | Cerebrospinal Fluid Kappa Free Light Chain Index | Molecular Type | Protein (Immunoglobulin Fragment) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis |
| Disease | Multiple Sclerosis | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | CSF (Immunoturbidimetry) | ||
| Pathobiological Mechanisms | Reflects intrathecal immunoglobulin synthesis, with sensitivity comparable to OCBs, and more convenient detection. | ||||
| Clinical Availability Status | Research validation / early clinical use: Some guidelines recommend replacing OCBs in resource-limited areas. | ||||
| Notes and Dynamics | Combined use with OCBs can improve diagnostic sensitivity and reduce missed diagnoses. | ||||