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543

Parameter
Biomarker Exo miR-126 Full name Exosomal MicroRNA-126 Molecular Type Non-coding RNA (miRNA)
Molecular Formula / Molecular Weight / Core Functional Dimensions Monitoring, Prognosis
Disease Multiple Sclerosis Disease Subtypes /
Organ Brain Test Sample / Technology Platform Serum / Urine (RT-qPCR)
Pathobiological Mechanisms Regulates vascular endothelial function and insulin signaling, decreased levels exacerbate blood-brain barrier injury and inflammatory infiltration.
Clinical Availability Status Cutting-edge research: Positively correlated with MRI lesion load, a potential hotspot for non-invasive monitoring.
Notes and Dynamics Can be detected through liquid biopsy, avoiding repeated MRI, suitable for long-term follow-up.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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