Parameter
| Biomarker | Akkermansia muciniphila | Full name | Akkermansia muciniphila | Molecular Type | Microorganism (Bacterium) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Susceptibility, Monitoring |
| Disease | Multiple Sclerosis | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Feces (16S rRNA Sequencing) | ||
| Pathobiological Mechanisms | Regulates intestinal barrier integrity and immune balance; decreased abundance leads to lipopolysaccharide leakage, aggravating systemic inflammation. | ||||
| Clinical Availability Status | Cutting-edge research: Abundance is significantly lower in MS patients than in healthy individuals, associated with Th17/Treg imbalance. | ||||
| Notes and Dynamics | Probiotic supplementation can increase its abundance; related clinical trials are exploring the therapeutic potential of gut microbiota intervention. | ||||