Parameter
| Biomarker | SCFAs | Full name | Short-Chain Fatty Acids (Acetate, Propionate, Butyrate) | Molecular Type | Microorganism (Bacterium) |
|---|---|---|---|---|---|
| Molecular Formula | C2H4O2/C3H6O2/C4H8O2 | Molecular Weight | 60.05/74.08/88.11 g/mol | Core Functional Dimensions | Susceptibility, Monitoring |
| Disease | Multiple Sclerosis | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Serum / Feces (GC-MS) | ||
| Pathobiological Mechanisms | Intestinal microbiota fermentation products, regulate immune cell differentiation; decreased levels weaken anti-inflammatory effects and blood-brain barrier stability. | ||||
| Clinical Availability Status | Cutting-edge research: Acetate and propionate levels are decreased in MS patients, negatively correlated with NfL levels. | ||||
| Notes and Dynamics | Can be increased through dietary fiber intervention, a potential target for dietary adjuvant therapy. | ||||