Parameter
| Biomarker | NPTX2 | Full name | Neuronal Pentraxin 2 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Disease Monitoring, Prognosis |
| Disease | Frontotemporal Dementia | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | CSF (ELISA, WB) | ||
| Pathobiological Mechanisms | A presynaptic protein involved in synaptic plasticity, decreased in FTD due to synaptic injury. | ||||
| Clinical Availability Status | Research exploration stage | ||||
| Notes and Dynamics | One of the earliest abnormal CSF biomarkers in FTD; decreased 5 years before symptoms in GRN mutation carriers, negatively correlated with frontotemporal synaptic density. | ||||