Parameter
| Biomarker | miR-124 | Full name | MicroRNA-124 | Molecular Type | Non-coding RNA (microRNA) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Subtype Differentiation |
| Disease | Frontotemporal Dementia | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Plasma/Prefrontal Cortex (qPCR, RNA-seq) | ||
| Pathobiological Mechanisms | Regulates neurogenesis and synaptic function; plasma levels are decreased in FTD due to neuronal injury. | ||||
| Clinical Availability Status | Research stage | ||||
| Notes and Dynamics | Plasma miR-124 distinguishes FTD from AD, positively correlated with executive function scores in bvFTD. | ||||