Parameter
| Biomarker | [18F]-FDG (PET) | Full name | [18F]-FDG (Glucose Metabolism PET Imaging) | Molecular Type | Imaging Biomarker |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Pathological Confirmation |
| Disease | Frontotemporal Dementia | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Brain (PET Imaging) | ||
| Pathobiological Mechanisms | Reflects neuronal function; glucose metabolism is decreased in the frontotemporal lobe of FTD patients. | ||||
| Clinical Availability Status | Clinical auxiliary diagnosis | ||||
| Notes and Dynamics | Orbital frontal cortex metabolism is decreased by 40% in bvFTD patients; left temporal lobe metabolism is decreased by 35% in svPPA patients, negatively correlated with plasma NfL. | ||||