Parameter
| Biomarker | FRZB | Full name | Frizzled-Related Protein (Wnt Antagonist) | Molecular Type | Protein (Wnt Antagonist) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Disease Monitoring |
| Disease | Amyotrophic Lateral Sclerosis | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Plasma/Skeletal Muscle (ELISA, Immunohistochemistry) | ||
| Pathobiological Mechanisms | Secreted increased after muscle denervation, inhibits the Wnt pathway, affecting muscle regeneration. | ||||
| Clinical Availability Status | Research exploration stage | ||||
| Notes and Dynamics | Positively correlated with the degree of myofiber atrophy; oral probiotics can downregulate FRZB levels and improve muscle function. | ||||