Parameter
| Biomarker | TERT Promoter Mut | Full name | TERT Promoter Mutation | Molecular Type | Gene Mutation |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Prognosis, Diagnosis |
| Disease | Glioblastoma | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Tumor Tissue (NGS, Pyrosequencing) | ||
| Pathobiological Mechanisms | Promoter mutations enhance telomerase activity, maintaining the unlimited proliferation capacity of tumor cells. | ||||
| Clinical Availability Status | Under clinical validation | ||||
| Notes and Dynamics | The mutation rate exceeds 70% in primary GBM, associated with poor prognosis in IDH wild-type GBM. | ||||