Parameter
| Biomarker | MIF | Full name | Macrophage Migration Inhibitory Factor | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Monitoring, Prognosis |
| Disease | Glioblastoma | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Tumor Tissue/Cerebrospinal Fluid (ELISA, Western Blot) | ||
| Pathobiological Mechanisms | Activates the NF-κB pathway, promotes microglial activation, angiogenesis, and immunosuppression, enhancing tumor invasion. | ||||
| Clinical Availability Status | Under clinical validation | ||||
| Notes and Dynamics | The MIF inhibitor ISO-1 can inhibit GBM cell proliferation, and combined with TMZ can improve chemotherapy efficacy. | ||||