Parameter
| Biomarker | ApoE | Full name | Apolipoprotein E (Gene Polymorphism) | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Prognosis, Prediction |
| Disease | Glioblastoma | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Plasma/Tumor Tissue (ELISA, Gene Sequencing) | ||
| Pathobiological Mechanisms | The ApoE4 subtype promotes tumor invasion by regulating lipid metabolism, inhibits the anti-tumor activity of CD8+T cells. | ||||
| Clinical Availability Status | Research validation stage | ||||
| Notes and Dynamics | ApoE mimetic peptides can improve the tumor immune microenvironment and enhance the efficacy of PD-1 inhibitors. | ||||