Parameter
| Biomarker | Syntenin-1 (SDCBP) | Full name | Syntenin-1 (SDCBP) | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Monitoring, Prognosis |
| Disease | Glioblastoma | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Tumor Tissue/Plasma (ELISA, IHC) | ||
| Pathobiological Mechanisms | Binds to syndecan to activate the PI3K/AKT pathway, maintains cancer stem cell characteristics, and promotes invasive metastasis. | ||||
| Clinical Availability Status | Research validation stage | ||||
| Notes and Dynamics | Inhibitors of the PDZ1 domain can reduce GBM cell invasiveness and reduce intracerebral metastasis in animal models. | ||||