Parameter
| Biomarker | MALAT1 | Full name | MALAT1 (Long Non-Coding RNA) | Molecular Type | lncRNA |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Monitoring, Prognosis |
| Disease | Glioblastoma | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Tumor Tissue/Plasma (qRT-PCR, RNA-seq) | ||
| Pathobiological Mechanisms | Regulates EZH2-mediated epigenetic silencing, promotes tumor angiogenesis and epithelial-mesenchymal transition (EMT). | ||||
| Clinical Availability Status | Research stage | ||||
| Notes and Dynamics | Plasma MALAT1 levels are positively correlated with tumor recurrence risk, serving as a liquid biopsy monitoring biomarker. | ||||