Parameter
| Biomarker | POFUT1 | Full name | Protein O-Fucosyltransferase 1 | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Prediction |
| Disease | Glioblastoma | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Tumor Tissue (IHC, qRT-PCR) | ||
| Pathobiological Mechanisms | Regulates the Notch signaling pathway, maintaining the self-renewal ability of cancer stem cells. | ||||
| Clinical Availability Status | Research stage | ||||
| Notes and Dynamics | POFUT1 inhibitors can enhance TMZ sensitivity and inhibit GBM cell proliferation in vitro experiments. | ||||