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593

Parameter
Biomarker GSDMB Full name Gasdermin B Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis, Prognosis
Disease Glioblastoma Disease Subtypes /
Organ Brain Test Sample / Technology Platform Tumor Tissue (IHC, Western Blot)
Pathobiological Mechanisms Mediates pyroptosis, regulates the tumor immune microenvironment, and high expression indicates a better prognosis.
Clinical Availability Status Research stage
Notes and Dynamics GSDMB expression is positively correlated with CD8+T cell infiltration, serving as a predictive biomarker for immunotherapy efficacy.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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