Parameter
| Biomarker | MMN | Full name | Mismatch Negativity | Molecular Type | Neurophysiological Indicator |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Susceptibility, Pharmacodynamics/Response |
| Disease | Schizophrenia | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Scalp Electroencephalogram (EEG, TF-ERP Analysis) | ||
| Pathobiological Mechanisms | Reflects NMDAR functional abnormalities and excitation-inhibition imbalance, early auditory processing disorders, and is associated with cognitive deficits. | ||||
| Clinical Availability Status | Research validation stage | ||||
| Notes and Dynamics | Cross-species (human/rodent) validated, can be used as a target engagement biomarker for NMDAR-targeted therapy. | ||||