Parameter
| Biomarker | BDNF | Full name | Brain-Derived Neurotrophic Factor | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Prognosis, Monitoring, Pharmacodynamics/Response |
| Disease | Schizophrenia | Disease Subtypes | / | ||
| Organ | Brain | Test Sample / Technology Platform | Plasma/Serum (ELISA, SIMOA) | ||
| Pathobiological Mechanisms | Decreased neuroplasticity, impaired neuronal survival and differentiation, synaptic dysfunction, and levels can be upregulated after treatment. | ||||
| Clinical Availability Status | Under clinical validation | ||||
| Notes and Dynamics | Positively correlated with cognitive function; levels are significantly decreased in treatment-resistant patients. | ||||