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Parameter
Biomarker SHP2 Full name Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 2 Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Diagnosis and pathogenesis-related
Disease Autoimmune Disease (AD) Disease Subtypes /
Organ Spleen, thymus, lymphoid tissue Test Sample / Technology Platform Plasma (ELISA)
Pathobiological Mechanisms Elevated plasma levels, associated with clinical laboratory features, promote lupus progression。
Clinical Availability Status Research verification: Inhibitors can improve tissue damage and immune dysfunction in lupus mice
Notes and Dynamics Closely associated with the pathogenesis of SLE, it also holds potential as a diagnostic and therapeutic target.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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