Parameter
| Biomarker | aCL | Full name | Anti-Cardiolipin Antibodies | Molecular Type | Protein (autoantibody) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, Thrombosis/acute pregnancy risk assessment |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Serum (ELISA) | ||
| Pathobiological Mechanisms | The target antigen is cardiolipin, with subtypes including IgG, IgM, and IgA. | ||||
| Clinical Availability Status | Clinically available: Persistent positivity at medium to high titers is a critical diagnostic criterion for APS. | ||||
| Notes and Dynamics | IgG subtypes show strongest association with thrombosis and adverse pregnancy outcomes. | ||||