Parameter
| Biomarker | Anti-RoSSA antibody | Full name | Anti-Ro/SSA antibody (Ro52/Tripartite Motif Containing 21, Ro60/SSA) | Molecular Type | Protein (autoantibody) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, disease association |
| Disease | Autoimmune Disease (AD) | Disease Subtypes | / | ||
| Organ | Spleen, thymus, lymphoid tissue | Test Sample / Technology Platform | Serum (immunological assay) | ||
| Pathobiological Mechanisms | Participates in immune regulation; target of autoimmune response in salivary glands. | ||||
| Clinical Availability Status | Clinically available; positive rate reaches 60%-80% in pSS cases, sensitivity of 75%-85% for early screening, and specificity >88%. | ||||
| Notes and Dynamics | Core serological marker; associated with extraglandular manifestations. | ||||