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88

Parameter
Biomarker CIP2A Full name Cancerous Inhibitor of Protein Phosphatase 2A Molecular Type Protein
Molecular Formula / Molecular Weight / Core Functional Dimensions Prognosis, prediction of treatment failure
Disease Chronic Myeloid Leukemia(CML) Disease Subtypes /
Organ Blood, bone marrow Test Sample / Technology Platform Diagnostic sample (protein level detection)
Pathobiological Mechanisms Overexpression is associated with disease progression and treatment failure, with this effect observed only in patients treated with dasatinib.
Clinical Availability Status Research validation: Clinical trials have confirmed its association with progression-free survival and treatment failure rate.
Notes and Dynamics It can serve as a simple and feasible diagnostic biomarker, providing a reference for the formulation of therapeutic strategies.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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