Parameter
| Biomarker | LDH | Full name | Lactate Dehydrogenase | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, prognosis, and treatment monitoring |
| Disease | Chronic Myeloid Leukemia(CML) | Disease Subtypes | / | ||
| Organ | Blood, bone marrow | Test Sample / Technology Platform | Peripheral blood (GeneXpert RT-PCR, ROC curve analysis) | ||
| Pathobiological Mechanisms | Strongly positively correlated with BCR-ABL transcription levels, with a significant decrease observed post-treatment | ||||
| Clinical Availability Status | Clinical validation: AUC of 0.881, superior to indicators such as uric acid and platelets. | ||||
| Notes and Dynamics | Economically viable, it can serve as an alternative diagnostic marker, prognostic biomarker, and potential therapeutic target. | ||||