Parameter
| Biomarker | miR-20/miR-106/miR-222 | Full name | microRNA-20/microRNA-106/microRNA-222 | Molecular Type | Nucleic acid (miRNA) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, prognosis |
| Disease | Chronic Myeloid Leukemia(CML) | Disease Subtypes | / | ||
| Organ | Blood, bone marrow | Test Sample / Technology Platform | Plasma (real-time quantitative RT-PCR) | ||
| Pathobiological Mechanisms | Significantly upregulated in newly diagnosed CML patients, targeting the regulation of cell cycle, MAPK and other related pathways. | ||||
| Clinical Availability Status | Research verification: upregulated by 17.4-fold, 19-fold, and 74.95-fold respectively, with statistical significance. | ||||
| Notes and Dynamics | Provide a theoretical basis for the diagnosis and prognosis evaluation of CML. | ||||