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94

Parameter
Biomarker MALAT1 Full name Metastasis-Associated Lung Adenocarcinoma Transcript 1 Molecular Type Nucleic acid (lncRNA)
Molecular Formula / Molecular Weight / Core Functional Dimensions Dassatinib resistance prediction
Disease Chronic Myeloid Leukemia(CML) Disease Subtypes /
Organ Blood, bone marrow Test Sample / Technology Platform Patient samples (bioinformatics analysis, differential expression gene screening)
Pathobiological Mechanisms May exert tumor-suppressive effects and be associated with the development of dafatinib resistance in CML
Clinical Availability Status Research validation: Predicting their functions by constructing lncRNA-miRNA-mRNA networks.
Notes and Dynamics To provide guidance for the research on the resistance mechanism of dasatinib and the development of therapeutic targets.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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