Parameter
| Biomarker | CD203c | Full name | Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 3 | Molecular Type | Protein (surface antigen) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Diagnosis, treatment, and monitoring |
| Disease | Chronic Myeloid Leukemia(CML) | Disease Subtypes | / | ||
| Organ | Blood, bone marrow | Test Sample / Technology Platform | Peripheral blood (flow cytometry) | ||
| Pathobiological Mechanisms | Specifically expressed in basophils, overexpressed in CML patients, and significantly reduced after treatment. | ||||
| Clinical Availability Status | Research Verification: Associated with disease risk characteristics, upregulated IgE receptor cross-linking. | ||||
| Notes and Dynamics | The changes in the number of basophils can be evaluated during the diagnostic and treatment phases. | ||||