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Parameter
Biomarker CCAT2 Full name Colon Cancer Associated Transcript 2 Molecular Type Nucleic acid (lncRNA)
Molecular Formula / Molecular Weight / Core Functional Dimensions Imatinib treatment response prediction
Disease Chronic Myeloid Leukemia(CML) Disease Subtypes /
Organ Blood, bone marrow Test Sample / Technology Platform Peripheral blood mononuclear cells (real-time reverse transcription PCR)
Pathobiological Mechanisms Highly expressed in CML patients, associated with treatment response, spleen volume, and EUTOS score
Clinical Availability Status Research verification: High expression associated with imatinib resistance.
Notes and Dynamics Can serve as a molecular biomarker for predicting treatment response in chronic-phase CML patients.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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