Parameter
| Biomarker | ASF1A | Full name | Anti-Silencing Function 1A Histone Chaperone | Molecular Type | Protein |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Disease progression prediction, therapeutic targets |
| Disease | Chronic Myeloid Leukemia(CML) | Disease Subtypes | / | ||
| Organ | Blood, bone marrow | Test Sample / Technology Platform | Bone marrow samples (expression level detection, functional experiments) | ||
| Pathobiological Mechanisms | Mediates cell differentiation arrest, promotes the transformation of CML into the acute phase, and activates the Notch signaling pathway | ||||
| Clinical Availability Status | Research verification: abnormally elevated levels in patients during the acute phase. | ||||
| Notes and Dynamics | Targeting ASF1A May Become a Novel Strategy for CML Treatment | ||||