Parameter
| Biomarker | miR-495-3p | Full name | microRNA-495-3p | Molecular Type | Nucleic acid (miRNA) |
|---|---|---|---|---|---|
| Molecular Formula | / | Molecular Weight | / | Core Functional Dimensions | Drug resistance prediction, therapeutic targets |
| Disease | Chronic Myeloid Leukemia(CML) | Disease Subtypes | / | ||
| Organ | Blood, bone marrow | Test Sample / Technology Platform | Cell models/patient samples (expression level detection, functional experiments) | ||
| Pathobiological Mechanisms | Downregulation of expression leads to TKI resistance, and drug efflux is inhibited by regulating MDR1. | ||||
| Clinical Availability Status | Research verification: overexpression inhibits the growth of drug-resistant cells. | ||||
| Notes and Dynamics | May serve as a therapeutic target to reverse TKI resistance. | ||||