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131

Parameter
Biomarker SH3GL1 Full name SH3 domain containing GRB2 like 1 Molecular Type Protein
Molecular Formula Molecular Weight Core Functional Dimensions Prognosis, therapeutic targets
Disease Non-Hodgkin Lymphoma (NHL) Disease Subtypes /
Organ Lymphoid tissue Test Sample / Technology Platform Tissues, cell lines (immunohistochemistry, CRISPR editing)
Pathobiological Mechanisms High expression inhibits ferroptosis and adriamycin resistance, associated with poor prognosis
Clinical Availability Status Research validation phase: 126 patients and cell experiment validation, requiring dynamic monitoring and drug development
Notes and Dynamics Developing detection antibodies and exploring targeted ferroptosis combined with chemotherapy strategies.

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This study was supported by the Scientific Research Innovation Capability Support Project for Young Faculty (SRICSPYF-ZY2025112), the Fundamental and Interdisciplinary Disciplines Breakthrough Plan of the Ministry of Education of China (JYB2025XDXM612)

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